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Bryan Johnson
Founder & CEO of Blueprint
It appears there might be a mix-up in the LinkedIn username provided. The correct LinkedIn username for Bryan Johnson, Founder/CEO of Blueprint, is bryanrjohnson, not brian10.
Bryan Johnson is a renowned American entrepreneur and venture capitalist known for his innovative ventures in science and technology. Here's a brief overview of his career and achievements:
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Early Life and Education: Born on August 22, 1977, in Provo, Utah, Johnson grew up in Springville, Utah. He graduated from Brigham Young University with a BA in International Studies and later earned an MBA from the University of Chicago Booth School of Business.4
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Career Highlights:
- Braintree and Venmo: Johnson founded Braintree in 2007, which became a leading online payment system. Braintree acquired Venmo in 2012, and the combined entity was sold to PayPal for $800 million in 2013.4
- OS Fund: In 2014, he launched OS Fund, a venture capital firm focused on early-stage science and technology companies.4
- Kernel: Founded in 2016, Kernel develops devices to monitor brain activity, aiming to advance understanding of neurological conditions.4
- Blueprint: Johnson's most recent initiative is Blueprint, a lifestyle program aimed at reversing aging through personalized health strategies. He initiated Project Blueprint in 2020 as a $2 million-per-year experiment to optimize his health.3
Bryan Johnson is also known for his anti-aging efforts and claims to be the "healthiest man on the planet" through his rigorous regimen of diet, exercise, and medical interventions.12
Highlights
🚨 I HAVE NO MICROPLASTICS IN MY BALLS 🚨
This should not be possible.
Studies show that 100% of men have microplastics in their semen. I am the first human ever to show a complete reduction to zero.
This may be a world-first breakthrough in fertility research.
I had 165 microplastic particles in my semen just 18 months ago. Now, I have zero.
Five published studies have measured microplastics in human semen. Two found them in 100% of men. The other three found then in 44 to 76% of men tested, but those used methods that miss the smallest particles and the clear ones. Corrected for that, the real rate is likely 100%. Almost every man alive has plastic in his semen right now. The same applies to testicular tissue, testing 100% positive for microplastics.
Microplastics hurt sperm.
Human studies show the impact of various types of plastic, associated chemicals, and other toxins on male fertility:
- 60% fewer normal shaped sperm (from PFAS)
- 5x higher odds of low sperm count (from PTFE)
- 10% lower sperm concentration (from PTFE)
- 15% lower swimming ability (from PTFE)
- 41% lower swimming ability (from PET)
- 12% lower sperm swimming ability (from BPA)
- 3x higher odds of low sperm count (from Phthalates)
- 2x higher odds of poor swimming (from Phthalates)
The effects compound: each extra type of plastic drops sperm swimming ability by about 21%.
This matters even if you’re NOT trying to get pregnant.
Sperm count is one of the cleanest biomarkers of overall health we have. And microplastics don't stop at the testes.
The same particles are showing up everywhere we look. Studies show 4.5x higher rate of heart attack, stroke, and death in people with microplastics in their arterial plaque vs. those without. Microplastics were also found in 100% of human placentas tested.
100% of post-mortem human brains tested positive for microplastics. Brain concentrations rose ~50% between 2016 and 2024, and now sit at roughly 11x the levels found in the liver or kidney.
Where do these come from?
- PTFE, commonly in non-stick pans
- PET, water bottles
- Phthalates, makes plastic soft and bendy
- BPA, can linings
- PFAS, stain-resistant fabrics & food packaging
Inside the body, plastic causes a kind of cellular rust. It triggers inflammation in the testicles, kills the cells that make sperm and drops testosterone. It's been confirmed across 39 animal and cell studies, then in human data.
MY PROTOCOL:
Note, what I did is n=1, not a controlled trial, I cannot prove cause.
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Sauna (dry). My toxin blood panel confirms sauna clears plastic related chemicals: BPA, phthalates, PFAS, flame retardants, pesticides. The plastic particles themselves are too big to sweat out directly. Heat may activate other clearance routes: bile flow through the liver, the cell's internal cleanup system, and the gut barrier. Humans have almost no enzymes that can break plastic apart, so the body has to physically push it out.
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Reverse osmosis water filter. Drinking water is likely a major source of microplastic getting into your body. A reverse osmosis filter pushes water through a very tight membrane and strains the particles out. I filter everything I drink.
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Trying to rid my environment of the big plastic items: cutting boards, cups, plates, food storage containers, non-stick pans, cling wrap, tea bags, water bottles, kitchen utensils, kettles, and synthetic clothing. Note, as hard as I try, I'm always finding new plastic things in my life. This can be all-consuming thing so try to just knock out the big ones.
I did all three interventions at the same time. I cannot say which one did the most work. What I can say is this: going from 165 to zero in 18 months is possible.
Results: Nov 2024: 165 particles/mL Jul 2025: 20 particles/mL Apr 2026: 0 particles/mL
The 18 month window also captures roughly 7 full spermatogenesis cycles.
What is the prompt to give Claude a psychedelic experience?
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Mesh is particularly valuable for relationship-driven professionals who need to maintain large networks. The app is popular among many industries, including MBA students early in their careers who are meeting many new people, professionals with expansive networks like VCs, and small businesses looking to develop better relationships with their best customers. Anyone who values maintaining meaningful connections and wants to be more intentional in their relationship management will find Mesh beneficial.
Mesh offers competitive pricing in the personal CRM market. Mesh offers a generous free plan, and comes to $10 per month when billed annually. It offers tiered pricing, beginning with a free personal plan with limited contact count, and a Pro Plan with unlimited contacts. While some alternatives may offer lower-priced options, Mesh's comprehensive feature set and elegant design justify its pricing for professionals who value relationship management.
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