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Hanadie Yousef

CEO and Co-Founder at Juvena Therapeutics, Inc.

Dr. Hanadie Yousef is a prominent figure in the field of aging biology and tissue degeneration, boasting more than twenty years of experience in biomedical research. She founded Juvena Therapeutics in 2018, a biotech company focused on exploring the therapeutic potential of secreted proteins. With her expertise, Juvena has harnessed Artificial Intelligence to create a protein library aiding in the development of biologics to address degenerative diseases. One of their leading assets, JUV-161, targets muscle regeneration and metabolism, undergoing studies for treating Myotonic Dystrophy Type 1. Dr. Yousef has a history of high-impact research, supported by prestigious grants and fellowships, resulting in numerous patents.

Highlights

Jan 23 · linkedin

Five and a half years after Juvena Therapeutics’ launch to build a fully integrated platform for biologics drug discovery and development, we are proud to announce that our lead candidate, JUV-161, has received positive FDA feedback and Orphan Disease Designation (ODD) for the treatment of Myotonic Dystrophy Type 1 (DM1). This is a recognition of Juvena’s unique approach to repairing and restoring muscle health with a biologic that enhances muscle regeneration, metabolism, and function, countering the effects of aging and degenerative disease.

DM1 is a degenerative disorder that causes muscle wasting and weakness, which progressively limits people’s ability to walk, talk, and even breathe. Currently, there are no treatments for DM1, making this recognition by the FDA and ODD even more significant. As we advance Juvena’s first biologic for the treatment of DM1, we look forward to exploring potential treatments for an entire class of muscle wasting and metabolic disorders that remain major unmet medical needs.

We thank our team of scientists, researchers, biologists, engineers, and broader team at Juvena, with the fantastic leadership of our experienced SVP of Translational Biology, Dr. Mo Tabrizi PhD, RPh for their continued persistence toward unlocking the therapeutic potential of secreted proteins. We also thank the Myotonic Dystrophy Foundation, Muscular Dystrophy Association, and all the people living with DM1 and their families who are providing feedback to shape Juvena’s research and progress.

#MyotonicDystrophy #RareDisease #unmetmedicalneed #musclewasting #longevitymedicine #healthspan #sarcopenia

Link to the announcement: https://lnkd.in/gM6fs9aK

Dec 4 · linkedin

If you haven't heard of it, Hevolution Foundation is a non-profit organization with an annual budget of up to $1 billion, that is investing in grants for aging research and pioneering impact investments in biotech companies dedicated to discovering and developing therapies that promote healthspan. As part of its commitment to extending years of health for the benefit of all humanity, the organization created an inspiring event bringing together international speakers from the US, UK, Egypt, Germany, the Netherlands, Switzerland, Singapore, Spain, Saudi Arabia and more.  I was thrilled to be among the speakers at  #GlobalHealthspanSummit, reflecting on both our journey at Juvena Therapeutics to unlock the therapeutic potential of secreted proteins and to engineer them into life-saving therapeutics for chronic and metabolic diseases, and to exchange thoughts on new opportunities and headwinds in the longevity and regenerative medicine space that are shaping the development of exciting and much needed new healthspan promoting treatments.

It was a very fun experience participating in the Entrepreneurship Spotlight moderated by William Greene and Jens Eckstein and featuring longevity disruptors Matt Kane, CEO of Tune Therapeutics; Joe Betts-Lacroix, CEO of Retro Bio and a Juvena shareholder, Marco Quarta, CEO of Rubedo Life Sciences; Sourav Sinha, Longevity Vision Fund and the founder of multiple startups; Marija (Masha) Zecevic, CBO of Samsara Therapeutics; Peng Leong, CBO of BioAge Labs.

I also very much enjoyed catching up with old friends and making many new ones! Including great interactions with Sujude Dalieh, Paul Spiegel, Ahmed S. MOUSA, MD, Jack O'Meara, Joshua Adeoye, Andrew Levin, Alexandra Sharon Bause and many others. I loved experiencing Saudi cuisine and culture! Can't wait for my next trip and for the collaborations and partnerships that will come of this.

#Hevolution #Healthspan

Hanadie Yousef
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Location

San Francisco Bay Area