Suggestions
Jonathan O'Keeffe
CEO of Machine Medicine and expert in neurology and computational neuroscience
Jonathan O'Keeffe
Jonathan O'Keeffe is the CEO and Founder of Machine Medicine, a company building a platform for the development and deployment of precision neuro-therapeutics.12 He has a diverse background, including:
- Doctor of Medicine (MD) from the University of Oxford
- MSc in Machine Learning from University College London (UCL)
- PhD in Computational Neuroscience from the University of Cambridge
- Academic Clinical Fellow in Neurology at UCL
- Wellcome Trust Clinical Fellow at the University of Cambridge
As a practicing neurologist, O'Keeffe saw the limitations of treating patients one-by-one. He wanted to combine his neurology and computer science expertise to have a deeper impact. This led him to found Machine Medicine, which combines AI, clinical knowledge, and ambition to solve problems in neurology.2
Machine Medicine's first product is Kelvin, a motor assessment platform for Parkinson's disease and other movement disorders. Kelvin-PD is being used in major clinical trials today.1 The company is building the software and data layer for precision neuro-therapeutics like deep brain stimulation.3
O'Keeffe has an impressive educational background, including degrees from Oxford, Cambridge, UCL, and the Royal College of Physicians.1 He is a native English speaker with limited working proficiency in French.1
Highlights
Frankly pretty disgusting to see Labour introducing 20% VAT on private school fees. So, now parents who want to work hard to provide a better level of education for their children than the drivel supplied (as usual) by the state sector will be additionally penalised (in additional to paying taxes that ostensibly pay for a state school place for their children)... it is apparently not enough that they already pay twice... the effect is to make private education still more the preserve of the very wealthy instead of an option for the aspiring and ambitious (as it should be)...
I was delighted to see Machine Medicine's motor assessment platform, Kelvin, used to provide a distributed DBS service between the Mater in Dublin and St George's in London, here shown to be non-inferior to localised services. And a nod to the AI-powered services that we will provide in the future, to drive neuromodulation into a predictive and personalised paradigm in which its availability and efficacy will be 1000-Xed.
"Cloud-based secure video storage with standardised and easily catalogued levodopa challenge data ensures both sites have a clear view on factors important for prediction of outcome and influencing target selection, in our case using Kelvin by Machine Medicine, which also gives the potential of artificial intelligence to aid in standardised UPDRS III rating of video examinations which may reduce inter-rater variability in the future."
Congrats to Eoghan Donlon, Erlick Pereira, Richard Walsh and the rest of the teams at St. George's University Hospital, London, and the Mater Hospital, Dublin, for this sterling work.
