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Kaloyan Tsanov

Incoming Assistant Professor at University of Chicago | NIH K99/R00 Fellow at Memorial Sloan Kettering Cancer Center | cancer • epi/genetics • metastasis • stem cells

Kaloyan Tsanov is an accomplished professional with a diverse educational background in Biological and Biomedical Sciences. He holds a PhD and an AB in Molecular and Cellular Biology from Harvard University. He also studied Molecular Biology at Sofia University St. Kliment Ohridski and at the University of Otago. With a robust academic foundation, Kaloyan Tsanov has honed his expertise through various roles in prestigious institutions.

Highlights

Aug 23 · linkedin

Eighteen years ago, I came to the United States to pursue my dream of becoming a scientist. Last week marked a major milestone in this journey, as I accepted an Assistant Professor position at the University of Chicago, where I am thrilled to launch my own research group in January 2025!

The #TsanovLaboratory will tackle one of the biggest challenges in oncology – the lethal, stage IV, metastatic cancers. We will combine next-gen mouse models, functional genetics & multiomic approaches to understand and target the #drivers and #vulnerabilities of metastatic tumors, with the ultimate goal of much needed #therapies that are specifically tailored to #metastatic cancers. In doing so, I will be dedicated to #mentoring future generations of scientists and fostering a collegial, collaborative & inclusive culture of excellence, where everyone can reach their full potential while enjoying the journey of scientific discovery.

My deepest thanks go to my incredible mentors, colleagues, collaborators, sponsors & everyone who gave me a chance on the job market! 🙏 #LoweLab Memorial Sloan Kettering Cancer Center #DaleyLab #AndyMcMahonLab Harvard University #JaneCoffinChildsFund National Cancer Institute (NCI)

I excitedly look forward to joining the outstanding community at UChicago Medicine & University of Chicago Medicine Comprehensive Cancer Center, who have already made me feel most welcome. Will soon start building the team at all levels – details to follow! #newPI #nextchapter #cancerresearch #beatcancer

Jan 5 · linkedin

Metastatic stomach cancer remains a leading cause of cancer-related deaths worldwide, yet it is poorly understood due to the lack of tractable experimental models to study its underlying biology.

Today in Nature Cancer, we report a novel approach for recreating stomach cancer in laboratory models termed ‘EPO-GEMMs’. For the first time, we can take gene mutations seen in patients and directly introduce them in laboratory mice to produce genetically customized mouse ‘avatars’ of human stomach cancer in a matter of weeks. We anticipate that this platform will facilitate discovery efforts and accelerate the development of much needed therapies for this deadly but understudied disease.

This was a fantastic close collaboration with Dr. Josef Leibold (now at University of Tübingen) and Dr. Corina Amor (now at Cold Spring Harbor Laboratory), with contributions from other members of the Lowe laboratory (Memorial Sloan Kettering Cancer Center). #teamwork #stomachcancer #metastasis #EPOGEMMs

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Kaloyan Tsanov
Kaloyan Tsanov, photo 1
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Location

New York, New York, United States