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Michael McManus
Professor at University of California, San Francisco
Michael McManus is a distinguished researcher and academic at the University of California, San Francisco (UCSF). Here's a comprehensive overview of his career and accomplishments:
Academic Position and Affiliations
Michael T. McManus, Ph.D., currently holds the following positions:
- Full Professor in the Department of Microbiology and Immunology at UCSF2
- Vincent and Stella Coates Endowed Chair at UCSF23
- Member of the Helen Diller Comprehensive Cancer Center2
- Member of the Diabetes Center2
- Member of the Eli Edythe Broad Center for Regeneration Medicine and Stem Cell Research2
- Member of the Innovative Genomics Institute2
Research Focus and Expertise
Dr. McManus is an internationally recognized RNA biologist with expertise in several areas:
- Posttranscriptional gene regulation
- Small RNA-mediated regulation of gene expression
- Noncoding RNA
- Functional genomics
- Cancer biology
- CRISPR technology
- Mouse models of human disease124
His laboratory combines synthetic and systems biology approaches to study cancer biology using quantitative methods.2
Education and Training
- B.S. in Horticultural Science from Auburn University (1991)3
- Ph.D. in Biochemistry and Molecular Genetics from the University of Alabama at Birmingham (2000)3
- Postdoctoral training as a Cancer Research Institute Fellow at MIT, studying RNAi pathways in mammals under Nobel Laureate Phillip Sharp13
Career Progression at UCSF
- Assistant Professor (2004-2010)5
- Associate Professor (2010-2016)5
- Full Professor (2016-present)5
- Vincent and Stella Coates Endowed Chair (2012-present)5
Notable Achievements and Awards
Dr. McManus has received several prestigious awards for his innovative work and collaborative efforts:
- Sandler Integrative Science Award
- New Technologies Award
- PBBR Science Award
- Breakthrough Technologies Award
- WM Keck Award
- Robert J. Kleberg, Jr. and Helen C. Kleberg Award2
Research Impact
Michael McManus has made significant contributions to the scientific community, as evidenced by his extensive publication record and citation count:
- Cited by 37,876 researchers according to Google Scholar4
- Published numerous high-impact papers in prestigious journals such as Nature, Science, and Proceedings of the National Academy of Sciences4
His work has been particularly influential in areas such as epigenomics, gene silencing, RNA interference, and CRISPR technology.4

