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Patrick Lundgren

Investor at Hummingbird Ventures - Biotech

Patrick Lundgren is an investor and biotech incubation lead at Hummingbird Ventures, based in Boston, Massachusetts.1 He has an extensive background in biotech, immunology, and venture capital.

Education and Academic Achievements

Patrick holds impressive academic credentials:

  • PhD in Immunology from the University of Pennsylvania
  • MSc in Integrated Immunology from the University of Oxford (graduated with Distinction)
  • BA (Hons) in Natural Sciences from the University of Cambridge1

During his PhD, Patrick published over 10 papers in prestigious journals such as Cell, Nature, and Nature Metabolism.1 His research covered topics including adipocyte biology, immunology, and gut-brain signaling.

Professional Experience

Patrick's career spans various roles in biotech and venture capital:

  • Current Role: Investor at Hummingbird Ventures
  • Associate at Flagship Pioneering (August 2022 - Present)
  • Flagship Pioneering Fellow (June 2021 - August 2021)
  • Venture Fellow at Pear VC (2020 - 2021)
  • Co-Founder of NanoXCell Therapeutics (2018 - 2020)1

At Flagship Pioneering, he is involved in originating and building bioplatform companies.1 His experience at Pear VC included sourcing and analyzing startups in the biotech sector.

Entrepreneurial Ventures

As a co-founder of NanoXCell Therapeutics, Patrick worked on developing a non-viral nanotechnology platform aimed at creating single-cell CAR T cell therapies.1 This venture was backed by the University of Pennsylvania, National Science Foundation, and Johnson & Johnson.

Additional Information

Patrick is bilingual, with native or bilingual proficiency in both Swedish and English.1 His diverse background, which includes a summer research fellowship at NASA's Jet Propulsion Laboratory, demonstrates his multidisciplinary approach to science and innovation.

Highlights

Jan 8 · linkedin

Super excited to share that I'm joining Hummingbird Ventures, where I'll be focusing on backing outlier founders building the next generation of transformative companies in biotech/techbio.

To my colleagues and mentors at Flagship Pioneering, thank you for the countless growth opportunities, learnings, and relationships. It has been a privilege working together, and I look forward to staying in touch.

I’m in SF this week for JPM, would be great to catch up with old and new faces in my network if you are around! My new email is up and running, please do reach out: [email protected]

Oct 3 · linkedin

Happy to share one of the key papers from my PhD finally out, where we discover a mechanism whereby brown adipose tissue develops “thermogenic memory”.

One key thing I learned from this project is that some fields have advanced certain concepts and techniques much further than other fields, and using ideas that are relatively more advanced in one field and applying in a different field will likely put you in a good position to make interesting discoveries.

In the beginning of my PhD, we thought there were two concepts that were incredibly advanced in immunology that hadn’t really been studied in brown adipocyte biology: (1) cellular heterogeneity, and (2) memory.

The reasons were both technical and conceptual. Technical because adipocyte heterogeneity had been incredibly difficult to study since adipocytes couldn’t readily be encapsulated in droplets (given their large size and hydrophobicity) and phenotyped in traditional ways that for example immunologists love to phenotype cells (i.e. flow cytometry). Conceptual because memory hadn’t really been studied in the context of cold exposure.

A catalyst to solve the technical piece was the development of single nucleus RNA sequencing methods by a couple groups to profile the cellular heterogeneity of neurons (which are also very difficult cells to encapsulate into droplets). After optimizing this method for adipose tissue, we then applied this to the physiologically relevant setting of repeated cold exposure, integrated with spatial transcriptomics in parallel, and things got interesting. Check out the paper for the full story. It even includes a surprise appearance of acylcarnitines, which are really interesting metabolites, I promise. Thank you to all authors and collaborators. https://lnkd.in/eggF6nJ8

Related Questions

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Patrick Lundgren
Patrick Lundgren, photo 1
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Location

Boston, Massachusetts, United States