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Pawel Muranski

Assistant Professor Of Medicine; Director of Cellular Immunotherapy Program

Pawel Muranski is a physician-scientist specializing in tumor immunology and T cell-based adoptive immunotherapy for cancer and viral infections.2 He currently holds several positions at Columbia University Medical Center:

Professional Roles

  • Assistant Professor of Medicine, Pathology and Cell Biology34
  • Principal Investigator at the Columbia Center for Translational Immunology (CCTI)3
  • Director of Cellular Immunotherapy4

Research Focus

Dr. Muranski's work centers on:

  1. Basic science of tumor immunology
  2. Development of novel tumor- and virus-specific T cells for treating malignancies and refractory viral infections1

His research aims to initiate and execute early-phase clinical trials of adoptive immunotherapy at Columbia University Medical Center and NewYork-Presbyterian Hospital.

Notable Achievements

  • Developed polyoma-virus specific T (PyVST) cells targeting John Cunningham (JC) virus-related Progressive Multifocal Leukoencephalopathy (PML)1
  • Led a clinical trial of PyVSTs (NCT02694783) with promising results: 7/12 response rate and excellent safety record1

Laboratory

Dr. Muranski leads the Muranski Lab, which includes:

  1. A basic/translational research unit
  2. The Columbia Cellular Immunotherapy Laboratory (CITL), capable of clinical-grade manufacturing under current Good Manufacturing Practice (cGMP)1

His team explores various research areas, including the development of multi-epitope specific cytotoxic CD4+ T cells for treating cancers and refractory viral infections, as well as novel strategies for T cell-based therapy against SARS-CoV2 and related coronaviruses.1

Highlights

Sep 24 · healio.com
NewYork-Presbyterian, Columbia University appoint director of ...
Aug 30 · nyp.org
Dr. Pawel Muranski to Head New Cellular Immunotherapy ...
Dr. Pawel Muranski to Head New Cellular Immunotherapy ...

Related Questions

What are some of Dr. Muranski's most notable achievements in tumor immunology?
How has Dr. Muranski's work impacted the treatment of Progressive Multifocal Leukoencephalopathy (PML)?
What are the main goals of the Columbia Cellular Immunotherapy Laboratory (CITL)?
Can you provide more details on the clinical trials led by Dr. Muranski?
What innovative strategies is Dr. Muranski exploring for COVID-19 treatment?
Pawel Muranski
Pawel Muranski, photo 1
Pawel Muranski, photo 2
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Location

New York, New York