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Rene Bernards

Co-Founder at Oncosence

René Bernards is a Dutch cancer researcher and professor of molecular carcinogenesis at the Netherlands Cancer Institute in Amsterdam.37 He was born on January 4, 1953, in Bussum, Netherlands.2 Bernards is also a part-time professor of molecular carcinogenesis at Utrecht University.2510

Education and Career:

  • University of Amsterdam He studied medical biology.2
  • Leiden University He obtained a PhD in 1984 with a thesis on human adenoviruses.2
  • Whitehead Institute He was a post-doc under Robert Weinberg.2510
  • Harvard Medical School From 1988 to 1992, Bernards was an assistant professor.2510
  • Netherlands Cancer Institute In 1992, he became the head of the section of molecular carcinogenesis.29

Key Contributions and Research:

  • Bernards is known for his work on personal, DNA-based approaches to cancer treatment.2
  • He researches "escape routes" that tumors use to prevent effective medication use.2
  • He helped develop MammaPrint, a test to predict the likelihood of recurrent metastatic breast cancer and the necessity for chemotherapy after surgery.2349 MammaPrint is a 70-gene signature panel that identifies individuals at risk for early-stage breast cancer, allowing personalized prevention and treatment plans.4 Over 250,000 women have used MammaPrint to make treatment decisions.3
  • His lab uses functional genomic approaches to find cancer vulnerabilities that can be exploited therapeutically.36
  • Bernards's laboratory identified that the combination of a BRAF inhibitor and an EGFR inhibitor is effective for the treatment of BRAF mutant colon cancer.38
  • His research has produced 14 clinical trials.15

Entrepreneurship: Bernards has co-founded several biotechnology companies158:

  • Agendia (2003)158
  • Prolifix (1993, now TopoTarget)158
  • Qameleon Therapeutics158
  • Oncosence (2017)1810

Awards and Honors:

  • Fellow of the American Association for Cancer Research Academy (2018)249
  • International Honorary Member of the American Academy of Arts and Sciences (2019)24
  • Elected to the National Academy of Sciences (2020)79
  • Foreign Member of the Royal Society (2024)2
  • Royal Netherlands Academy of Arts and Sciences Academy Professor Prize (2013)24
  • Koningin Wilhelmina Onderzoeksprijs (2012)24
  • Spinoza Prize (2005)24
  • European Molecular Biology Organization member (1995)2
  • Pezcoller Foundation award349
  • Ernst Bertner Award for Cancer Research from the M.D. Anderson Cancer Center349
  • ESMO Lifetime Achievement Award349

Highlights

Dec 30 · agendia.com
Our Team - Agendia
Profile of Rene Bernards - PMC - PubMed Central
Jan 1 · royalsociety.org
Professor Rene Bernards ForMemRS - Royal Society
René Bernards Group | Oncode Institute
René Bernards Group | Oncode Institute
Professor Dr. Rene Bernards - Gilde Healthcare
May 7 · agendia.com
Agendia Co-Founder and Chief Scientific Officer René Bernards ...
High-Throughput Functional Genetic and Compound Screens ...
Oct 9 · en.wikipedia.org
René Bernards - Wikipedia

Related Questions

What are some of Rene Bernards' most significant contributions to cancer research?
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What are the key findings from Rene Bernards' laboratory at the Netherlands Cancer Institute?
Rene Bernards
Rene Bernards, photo 1
Rene Bernards, photo 2
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Location

Amsterdam, North Holland, Netherlands