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Simina Grigoriu

Principal Investigator at Roivant Sciences

Simina Grigoriu is a highly accomplished scientist specializing in structural biology and drug discovery.1 She currently holds the position of Associate Director of Protein & Structural Sciences at Accent Therapeutics, Inc.1 Prior to this role, she served as a Principal Investigator at Roivant Sciences from March 2021 to May 2022.1

Grigoriu has an extensive background in structural biology, with a focus on X-ray crystallography.1 She earned her Ph.D. in Structural Biology from Brown University, where her thesis explored the molecular basis of calcineurin inhibition by protein regulators.1

Throughout her career, Grigoriu has made significant contributions to drug discovery programs:

  1. At Roivant Sciences, she led scientific, technical, and operational aspects of structural biology for drug discovery programs.1
  2. She secured a competitive advantage for the company by generating the first-known structures of a high-profile target bound to chemical matter.1
  3. Grigoriu implemented a custom fragment screening workflow that enabled initial automated refinement of ~700 structures in one day.1
  4. She delivered over 100 novel ligand-bound structures as a Structural Biology functional lead for three portfolio programs.1

Her expertise extends to various techniques, including X-ray crystallography, cryo-EM, and HDX-MS, which she has applied to support hit finding, hit-to-lead, and lead optimization for portfolio projects.1

Highlights

Dec 13 · traxsource.com
Simina Grigoriu Tracks & Releases on Traxsource
Dec 1 · roivant.com
Leadership - Roivant
Nov 26 · soundcloud.com
Simina Grigoriu - SoundCloud
Nov 1 · leadiq.com
Roivant Sciences Employee Directory, Headcount & Staff | LeadIQ
Jan 31 · johngannonblog.com
VC Principal @ Roivant Sciences in Remote - John Gannon Blog
Oct 7 · en.wikipedia.org
Roivant Sciences - Wikipedia
Oct 31 · en.wikipedia.org
Simina Grigoriu - Wikipedia
Simina Grigoriu - Wikipedia

Related Questions

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Simina Grigoriu
Simina Grigoriu, photo 1
Simina Grigoriu, photo 2
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Location

Greater Boston