Suggestions
Zach Edge
Cannabinoids, Psychedelics, Small Molecule APIs
Zach Edge is an experienced entrepreneur and growth executive known for his work in active ingredients. With a background in psychology from The University of Texas at Austin, he has held key roles in several organizations such as Vice President of Business Development at Benuvia Manufacturing. Zach specializes in cannabinoid extraction, synthesis, purification, formulation, manufacturing, and co-packing. His expertise extends to cannabinoid and psychedelic APIs, including CBD, THC, CBG, and more. Zach's strong suit lies in strategic marketing, supply chain management, and identifying new business opportunities both nationally and internationally. Passionate about health and wellness, Zach has successfully launched and scaled multiple consumer products in various sectors like food, beverage, supplements, and cosmetics, always focusing on innovative ingredient selection and formulation.
Highlights
The law says what it says and it isn’t ambiguous.
“What’s your degree of certainty?”, you ask. I’m not uncertain.
Thanks Rod Kight for writing.
[7/20/24]bioRxiv & medRxiv :: Cannabidiol reverses fentanyl-induced addiction and modulates neuroinflammation :: Bidhan Bhandari, Henrique Izumi Shimaoka Chagas, Sahar Emami Naeini, Pablo Shimaoka Chagas, Ph.D, Hannah Rogers Davis, M.Ed., Jules Gouron, @Aruba Khan, @Lívia Maria Maciel, @Mohammad Seyyedi, @Neil J MacKinnon, Hesam Khodadadi, Évila da Silva Lopes Salles, @David C Hess, @John C Morgan, @Jack C Yu, @Lei P Wang, @Babak Baban
"We investigated if inhaled CBD could reverse the fentanyl addiction and whether the CBD treatment could ameliorate the addiction symptoms by regulating neuroinflammatory signals and re-establishing the homeostasis in CNS.
Method We used a fentanyl-induced conditioned place preference (CPP) model in mouse to test whether inhaled CBD could reverse the fentanyl addiction and ameliorate the adversarial symptoms. By employing a combination of flow cytometry as well as behavioral tests, we further assessed the impact of fentanyl addiction on cells and neuroinflammatory signals in CNS and we measured the effects of CBD in the treatment of addiction symptoms and inflammatory signals.
Results Our findings suggest that CBD inhalation could be used effectively in the treatment of fentanyl addiction. CBD mitigated the excessive fentanyl-induced neuroinflammatory responses and decreased cellular stress and senescence.
Conclusion inhaled CBD could alleviate the fentanyl addiction and regulate neuroinflammatory responses. This novel approach is non-invasive, accessible, effective, and warrants further, translational and research."
(Great find form Daniel Fowler, PhD)
